Article ID Journal Published Year Pages File Type
8361682 Regulatory Peptides 2011 9 Pages PDF
Abstract
►NPY secretion is regulated by leptin in two clonal hypothalamic cells lines. ►NPY is differentially regulated by activation of specific signaling pathways. ►Leptin activates AMPK to up-regulate NPY secretion. ►Leptin acts through MAPK and PI3K to suppress NPY secretion.
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Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Preview
Leptin differentially regulates NPY secretion in hypothalamic cell lines through distinct intracellular signal transduction pathways
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