Article ID Journal Published Year Pages File Type
8361703 Regulatory Peptides 2011 6 Pages PDF
Abstract
► GnRH stimulates synthesis of PACAP and PAC1R in gonadotroph. ► PACAP and PAC1R were preferentially induced by low frequency of GnRH pulse. ► PACAP produced from gonadotroph affects to gonadotroph through PAC1R. ► GnRH and PACAP coordinately work for FSHβ subunit synthesis.
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Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Preview
Possible involvement of PACAP and PACAP type 1 receptor in GnRH-induced FSH β-subunit gene expression
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