Article ID Journal Published Year Pages File Type
8361723 Regulatory Peptides 2011 9 Pages PDF
Abstract
► Sensory neurons in the rat bladder express TRPV1 and contain substance P. ► Systemic vanilloid administration may desensitise/destroy these neurons. ► Spinal cord and bladder TRPV1, SP and NK1 receptor expression changed after capsaicin and resiniferatoxin administration. ► Vanilloid administration may alter transcription and translation of TRPV1, SP and NK1 receptors.
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Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Preview
TRPV1, NK1 receptor and substance P immunoreactivity and gene expression in the rat lumbosacral spinal cord and urinary bladder after systemic, low dose vanilloid administration
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