Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8361869 | Seminars in Cancer Biology | 2017 | 40 Pages |
Abstract
Seven parameters: 1. Drug type, 2. tumor type, 3. presence of metastases or phenotypic change, 4. tumor cell number, 5. net growth rate (proliferation minus cell death), 6. inherited genetic- and 7. epigenetic- variations are crucial for drug responses. It is envisaged that it might become possible to calculate a clinically relevant Drug Resistance Index for Cancer (DRIC) for each patient.
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Authors
C.I. Edvard Smith,