| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8361893 | Seminars in Cancer Biology | 2017 | 21 Pages |
Abstract
In this review current knowledge on the characteristics of OCSCs and the micro environmental mechanisms leading to the development or activation of OCSCs resulting in ovarian cancer is reviewed. Moreover the role of OCSC in both surgical and systemic therapy resistance and the relation with epithelial mesenchymal transformation (EMT) is discussed, as are micro-environmental signals leading to OCSC or EMT activation.
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Biochemistry
Authors
Petronella Beatrix Ottevanger,