Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8366918 | Steroids | 2013 | 6 Pages |
Abstract
- We evaluated the validity of a commercial dihydrotestosterone (DHT) immunoassay.
- Immunoassay overestimated DHT concentrations by 79-1000% compared with LC-MS/MS.
- Immunoassay did not detect reductions in DHT following finasteride treatment.
- Cross-reactivity of the DHT immunoassay ranged from 18% to 99% with testosterone (T).
- This immunoassay is invalid for DHT assessment in biological fluids containing T.
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Authors
Joshua F. Yarrow, Darren T. Beck, Christine F. Conover, Luke A. Beggs, Bruce A. Goldberger, Stephen E. Borst,