Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8366934 | Steroids | 2013 | 9 Pages |
Abstract
- Synthesis of steroidal dendrimer conjugates of G1 and G2 with tetramethylene core.
- The conjugates and precursors were tested against a panel of cancer cell lines.
- The conjugates of G1 8 and 9 exhibit greater selectivity against CEM cells.
- 8 and 9 increase caspase 3 and 7 activity in leukemia cells (CEM).
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Authors
Nancy E. Magaña-Vergara, Lucie Rárová, Delia Soto-Castro, Norberto Farfán, Miroslav Strnad, Rosa Santillan,