| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8398032 | Toxicon | 2013 | 9 Pages |
Abstract
⺠ADP-ribosylating toxins mainly target proteins. However, pierisins ADP-ribosylates guanine residues in dsDNA. âºÂ SCO5461 protein, which shares homology with activity domains of MTX and pierisins, targets guanosine and deoxyguanosine. ⺠We discovered SCO5461 for the first time as an enzyme which modulates nucleosides. ⺠We discovered a possibly extracellular function of the ADP-ribosylation reaction.
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Authors
Tsuyoshi Nakano, Yuko Matsushima-Hibiya, Masafumi Yamamoto, Azusa Takahashi-Nakaguchi, Hirokazu Fukuda, Masaya Ono, Takeji Takamura-Enya, Haruyasu Kinashi, Yukari Totsuka,