Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8485075 | Tuberculosis | 2018 | 32 Pages |
Abstract
In conclusion, increased PMA during TB infection is caused by monocyte and not platelet activation. By counteracting the Mtb-induced pro-inflammatory leukocyte response, platelets may protect against excessive tissue damage, but may also compromise the production of protective cytokines, such as IFNƴ and TNFα.
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Authors
Vesla Kullaya, Andre van der Ven, Stellah Mpagama, Blandina T. Mmbaga, Philip de Groot, Gibson Kibiki, Quirijn de Mast,