| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8485284 | Tuberculosis | 2016 | 9 Pages |
Abstract
A total of 12 publications were included. We established that WGS has a higher discriminatory power compared to conventional genotyping and detects transmission events missed by epidemiological investigations. A cut-off value of <6 SNPs between isolates may predict recent transmission. None of the studies performed a head-to-head comparison between WGS and conventional genotyping using unselected prospectively collected isolates. Minimum reporting criteria for WGS studies have been proposed and quality control parameters considered.
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Authors
Vlad Nikolayevskyy, Katharina Kranzer, Stefan Niemann, Francis Drobniewski,