| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8507658 | Acta Pharmaceutica Sinica B | 2018 | 15 Pages |
Abstract
Chimeric antigen receptor T cells (CAR-T cells) are effector T cells processed from natural T cells by replacing the T cell receptor (TCR) part to CAR part which can recognize and eliminate tumor cells specifically. Their application has been made great progress in hematological malignancies, whereas various difficulties should be overcame in treating solid tumors. This review mainly focuses on the applications of CAR-T cells in different hematological malignancies.154
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Authors
Zijun Zhao, Yu Chen, Ngiambudulu M. Francisco, Yuanqing Zhang, Minhao Wu,