Article ID Journal Published Year Pages File Type
8507667 Acta Pharmaceutica Sinica B 2018 11 Pages PDF
Abstract
Downstream ERK kinase appears to be the Achilles' Heel of the MAPK pathway. Targeting ERK kinase provides potential therapeutic opportunities for a broad spectrum of cancers bearing RAS, RAF and MEK mutations as well as those with acquired resistance to BRAF and MEK inhibitors (RAFi and MEKi).109
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Health Sciences Pharmacology, Toxicology and Pharmaceutical Science Drug Discovery
Authors
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