| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8507668 | Acta Pharmaceutica Sinica B | 2018 | 12 Pages |
Abstract
Olmutinib could bind to ATP-binding cassette transporter subfamily G member 2 (ABCG2) ATP binding site, inhibit its drug efflux function, increase intracellular chemotherapeutic drug accumulation, and then restore sensitivity of multidrug resistance cells to ABCG2 substrate drug.298
Keywords
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Pharmacology, Toxicology and Pharmaceutical Science
Drug Discovery
Authors
Zhiqiang Zhang, Xiaoran Guo, Kenneth K.W. To, Zhen Chen, Xiaona Fang, Min Luo, Chunling Ma, Jianhua Xu, Shirong Yan, Liwu Fu,