| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8507768 | Acta Pharmaceutica Sinica B | 2018 | 11 Pages |
Abstract
In the present study, we demonstrated that 131I-evens blue (EB) could specifically bind to necrotic tissues image necrosis in living animals. Furthermore, the necrosis targeting mechanism of EB might be attributed to its binding to exposed DNA in necrotic areas.250
Keywords
HYPRCPDWIRFAT1WIT2WITLCCt-DNADMSOcalf-thymus DNAH&EDNA bindingMRIEvans BlueT1-weighted imagingT2-weighted imagingdiffusion-weighted imagingMagnetic resonance imagingradiofrequency ablationradiochemical purityDimethylsulfoxideRadioactivitymononuclear phagocyte systemSprague–Dawley ratsSD ratsMPshaematoxylin-eosinHypericinPropidium iodidethin layer chromatography
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Authors
Qiaomei Jin, Xin Shan, Qi Luo, Dongjian Zhang, Yuanyu Zhao, Nan Yao, Fei Peng, Dejian Huang, Zhiqi Yin, Wei Liu, Jian Zhang,