Co-existing colloidal phases in artificial intestinal fluids assessed by AF4/MALLS and DLS: A systematic study into cholate & (lyso-) phospholipid blends, incorporating celecoxib as a model drug

Article ID	Journal	Published Year	Pages	File Type
8511048	European Journal of Pharmaceutical Sciences	2018	37 Pages	PDF

Abstract

Separation of colloidal phases in artificial intestinal fluids by flow field-flow fractionation.88

Keywords

Vesicle sodium glycodeoxycholate t-BuOH MALLS FeSSIF FaSSIF GDx HIF AF4 SIF NTU DLS PDI PES PBS CPP DRI sn-glycero-3-phosphocholine Tertiary butanol Flow field-flow fractionation Asymmetrical flow field-flow fractionation Crossflow fed state simulated Intestinal fluid Celecoxib differential refractive index polydispersity index Simulated intestinal fluid Radius of gyration Phosphate buffered saline Phospholipid Intestinal fluid Human intestinal fluid Micelle Bile salt critical packing parameter Dynamic Light Scattering multi-angle laser light scattering multi-angle light scattering Polyether sulfone

Related Topics

Health Sciences Pharmacology, Toxicology and Pharmaceutical Science Drug Discovery

Co-existing colloidal phases in artificial intestinal fluids assessed by AF4/MALLS and DLS: A systematic study into cholate & (lyso-) phospholipid blends, incorporating celecoxib as a model drug

Authors

Philipp A. Elvang, Ann-Christin Jacobsen, Annette Bauer-Brandl, Paul C. Stein, Martin Brandl,