Evaluation and optimized selection of supersaturating drug delivery systems of posaconazole (BCS class 2b) in the gastrointestinal simulator (GIS): An in vitro-in silico-in vivo approach

Article ID	Journal	Published Year	Pages	File Type
8511685	European Journal of Pharmaceutical Sciences	2018	12 Pages	PDF

Keywords

supersaturation Precipitation Oral drug absorption Pharmacometrics In vivo In silico In vitro bioequivalence Oral bioavailability Microscopy Differential scanning calorimetry

Related Topics

Health Sciences Pharmacology, Toxicology and Pharmaceutical Science Drug Discovery

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Evaluation and optimized selection of supersaturating drug delivery systems of posaconazole (BCS class 2b) in the gastrointestinal simulator (GIS): An in vitro-in silico-in vivo approach

Authors

Bart Hens, Marival Bermejo, Yasuhiro Tsume, Isabel Gonzalez-Alvarez, Hao Ruan, Kazuki Matsui, Gregory E. Amidon, Katie L. Cavanagh, Gislaine Kuminek, Gail Benninghoff, Jianghong Fan, NaÃr RodrÃguez-Hornedo, Gordon L. Amidon,