| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8512498 | European Journal of Pharmaceutical Sciences | 2017 | 31 Pages |
Abstract
Four novel molecular salts of anti-tuberculosis drug ethionamide with various counter ions namely 2-chloro-4-nitrobenzoic acid, 2,6-dihydroxybenzoic acid, 2,3-dihydroxybenzoic acid and 2,4-dinitrobenzoic acid are reported. Physico-chemical properties associated with ETH-CNB, ETH-2,6HBA and ETH-2,3HBA are evaluated in the present study.127
Keywords
DSC2,4-Dinitrobenzoic acidDNBscXRDPXRDEthionamideAPICNBnuclear magnetic resonance2,3-dihydroxybenzoic acid2,6-dihydroxybenzoic acidethFourier transform infraredNMRRelative humiditySupramolecular chemistryFT-IRMolecular complexCrystal engineeringActive Pharmaceutical IngredientPharmaceutical saltsPowder X-Ray Diffractionsingle crystal X-ray diffractionDifferential scanning calorimetry
Related Topics
Health Sciences
Pharmacology, Toxicology and Pharmaceutical Science
Drug Discovery
Authors
Sunil Kumar Nechipadappu, Darshak R. Trivedi,