| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8512531 | European Journal of Pharmaceutical Sciences | 2017 | 49 Pages |
Keywords
MTDIMIPBPKaverage fold errorSMEp.o.MRTtmaxi.v.APIPACFirst in manCCClogarithm of the octanol/water partition coefficientlogPFrelFUPCmaxAFEQbDAUCCL/FFIMMTTImmediate releaseinnovative medicines initiativeBiopharmaceuticsAbsolute oral bioavailabilityclearanceApparent clearanceDose numberAbsorptionVolume of distributionapparent volume of distributionmaximal tolerated dosemaximum concentrationIntravenousper oralBCstime at maximum concentrationbioequivalencebiopharmaceutics classification systemconcordance correlation coefficientPearson correlation coefficientpharmacokineticFraction absorbedphysiologically-based pharmacokineticrelative bioavailabilityMatarea under the curveActive Pharmaceutical IngredientMean residence timeblood-to-plasma ratioMolecular weightDrug databasefraction unbound in plasmaQuality by designgastro-intestinal
Related Topics
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Pharmacology, Toxicology and Pharmaceutical Science
Drug Discovery
Authors
Adam S. Darwich, Alison Margolskee, Xavier Pepin, Leon Aarons, Aleksandra Galetin, Amin Rostami-Hodjegan, Sara Carlert, Maria Hammarberg, Constanze Hilgendorf, Pernilla Johansson, Eva Karlsson, Dónal Murphy, Christer Tannergren, Helena Thörn,