Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8512732 | Journal of Drug Delivery Science and Technology | 2018 | 9 Pages |
Abstract
Gossypol, gossypol-loaded Pluronic® F127 nanoparticles (GLPFNs) for intravenous (i.v.) administration were prepared and its pharmacokinetic and biodistribution studies were performed. The bioavailability of GLPFNs was enhanced by threefold after encapsulation, and higher uptake in RES organs was observed after i.v. administration of GLPFNs than gossypol alone.204
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Authors
Ying Wang, Ya Wang, Ji Wang, Wan Lei, Ke Li, Daocheng Wu, Xiaojuan Wang,