Article ID Journal Published Year Pages File Type
8512732 Journal of Drug Delivery Science and Technology 2018 9 Pages PDF
Abstract
Gossypol, gossypol-loaded Pluronic® F127 nanoparticles (GLPFNs) for intravenous (i.v.) administration were prepared and its pharmacokinetic and biodistribution studies were performed. The bioavailability of GLPFNs was enhanced by threefold after encapsulation, and higher uptake in RES organs was observed after i.v. administration of GLPFNs than gossypol alone.204
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