Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8513819 | Journal of Pharmaceutical Sciences | 2017 | 12 Pages |
Abstract
Solid-state studies of C-butyl-resorcin[4]arene with pregabalin (Lyrica, Nervalin) in nitrobenzene yielded a cocrystal of C-butyl-resorcin[4]arene with 4-isobutylpyrrolidone-2. A combined experimental and quantum chemical investigation was implemented to further our understanding of the factors affecting the conversion process.
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Authors
Amanda M. Drachnik, Harshita Kumari, Collin M. Mayhan, Drew A. Fowler, Wei G. Wycoff, Charles L. Barnes, John E. Adams, Carol A. Deakyne, Jerry L. Atwood,