Evaluation of novel formulations of d-Î²-hydroxybutyrate and melatonin in a rat model of hemorrhagic shock

Article ID	Journal	Published Year	Pages	File Type
8519610	International Journal of Pharmaceutics	2018	45 Pages	PDF

Keywords

DSC D-β-hydroxybutyrate HPβCD Lactated Ringer’s solution MLT SvO2 AAALAC IQR Tg′ALT UPLC-MS BHB PVP DMSO GC–MS AST Aspartate aminotransferase Alanine aminotransferase Alkaline phosphatase Antioxidant Time effect Group effect Venous oxygen saturation X-ray diffractometry Association for Assessment and Accreditation of Laboratory Animal Care International Ketone body BUN Room temperature Dimethyl sulfoxide Cyclodextrin Hemorrhagic shock mean arterial pressure Lyophilization interquartile range Melatonin map blood urea nitrogen Hydroxypropyl-β-cyclodextrin XRD Polyethylene glycol 400 PEG Differential scanning calorimetry

Related Topics

Health Sciences Pharmacology, Toxicology and Pharmaceutical Science Pharmaceutical Science

Evaluation of novel formulations of d-Î²-hydroxybutyrate and melatonin in a rat model of hemorrhagic shock

Authors

Andrea Wolf, Seema Thakral, Kristine E. Mulier, Raj Suryanarayanan, Gregory J Beilman,