Enhanced biopharmaceutical effects of tranilast on experimental colitis model with use of self-micellizing solid dispersion technology

Article ID	Journal	Published Year	Pages	File Type
8519751	International Journal of Pharmaceutics	2018	38 Pages	PDF

Keywords

IBD Self-micellizing solid dispersion PLM TNBS tranilast tmax SIR BMA MPC HCl DLS Cmax PBS 2-Methacryloyloxyethyl phosphorylcholine AUC MPO t1/2 hydrochloric acid Tem butyl methacrylate inflammatory bowel diseases Inflammatory bowel disease analysis of variance ANOVA maximum concentration Gastrointestinal BCs time to maximum concentration biopharmaceutics classification system selected ion recording pharmacokinetic Oral bioavailability Phosphate-buffered saline SEM myeloperoxidase Scanning electron microscopy Transmission electron microscopy Polarized light microscopy Half-life hematoxylin-eosin Solid dispersion Dynamic Light Scattering

Related Topics

Health Sciences Pharmacology, Toxicology and Pharmaceutical Science Pharmaceutical Science

Enhanced biopharmaceutical effects of tranilast on experimental colitis model with use of self-micellizing solid dispersion technology

Authors

Yoshiki Kojo, Hiroki Suzuki, Kouki Kato, Yuuki Kaneko, Kayo Yuminoki, Naofumi Hashimoto, Hideyuki Sato, Yoshiki Seto, Satomi Onoue,