Overcoming the polycation dilemma - Explorative studies to characterise the efficiency and biocompatibility of newly designed lipofection reagents

Article ID	Journal	Published Year	Pages	File Type
8520057	International Journal of Pharmaceutics	2018	36 Pages	PDF

Keywords

RFU Lipoplex pDNA IEP EtBr GAGs eGFP Lipofection FBS SDS supercoiled DPPE PBS tris-acetate-EDTA DLS 1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine 2-(N-morpholino)ethanesulfonic acid N/P ratio ethidium bromide Tem Transfection efficiency TAE supporting information open circular Cell viability sodium dodecyl sulphate fetal bovine serum Intensity Hydrodynamic radius Phosphate buffered saline Cationic lipids MeS Transmission electron microscopy Isoelectric point Haemocompatibility Relative Fluorescence Units Serum stability Dynamic Light Scattering enhanced green fluorescent protein Plasmid DNA DOPE Gene therapy Glycosaminoglycans

Related Topics

Health Sciences Pharmacology, Toxicology and Pharmaceutical Science Pharmaceutical Science

Overcoming the polycation dilemma - Explorative studies to characterise the efficiency and biocompatibility of newly designed lipofection reagents

Authors

Julia Giselbrecht, Christopher Janich, Shashank Reddy Pinnapireddy, Gerd Hause, Udo Bakowsky, Christian Wölk, Andreas Langner,