| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8522462 | Saudi Pharmaceutical Journal | 2018 | 14 Pages |
Abstract
The effect of supplementation of thirteen different antioxidants and their analogues as a single agent or in combination with chemotherapy has been compiled in this article. The present review encompasses a total of 174 peer-reviewed original articles from 1967 till date comprising 93 clinical trials with a cumulative number of 18,208 patients, 56 animal studies and 35 in vitro studies. Our comprehensive data suggests that antioxidant has superior potential of ameliorating chemotherapeutic induced toxicity. Antioxidant supplementation during chemotherapy also promises higher therapeutic efficiency and increased survival times in patients.
Related Topics
Health Sciences
Pharmacology, Toxicology and Pharmaceutical Science
Pharmaceutical Science
Authors
Kanchanlata Singh, Mustansir Bhori, Yasar Arfat Kasu, Ganapathi Bhat, Thankamani Marar,