Effects of cytochrome P450 single nucleotide polymorphisms on methadone metabolism and pharmacodynamics

Article ID	Journal	Published Year	Pages	File Type
8523892	Biochemical Pharmacology	2018	43 Pages	PDF

Keywords

MTD EMDP FDA MOR Cytochrome P450 (CYP)CyP EDDP HERG MMT ADH CDC NCBI μ-Opioid receptor Alcohol dehydrogenase deletion methadone maintenance treatment DEL Food and Drug Administration Cytochrome P450 Pharmacogenetics intermediate metabolizer extensive metabolizer poor metabolizer Methadone Centers for Disease Control and Prevention National Center for Biotechnology Information UTR یا untranslated regions untranslated region genetic variant Single nucleotide polymorphism (SNP)Single nucleotide polymorphism SNP human Ether-a-go-go Related Gene

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Effects of cytochrome P450 single nucleotide polymorphisms on methadone metabolism and pharmacodynamics

Authors

Taha Ahmad, Monica A. Valentovic, Gary O. Rankin,