Autophagy as a pharmacological target in hematopoiesis and hematological disorders

Article ID	Journal	Published Year	Pages	File Type
8523983	Biochemical Pharmacology	2018	80 Pages	PDF

Keywords

AMPK PI3K HSC SAR LSC MPP CMA SCD APL ATO mTOR Hsc70 FKBP MEP EPO MSC ERK CLP MIR MDS V-ATPase ETs GMP CML DMS cox2 CMP EFs HIF-1α SNARE ATG 3-MA GM-CSF IRS-1 SCF EBSS VAMP LAMP2A FOXO3 eIF4E TPO MLL HMOX1 DLBCL PBC TKI SGK1 M-CSF MVB mTORC ESCRT ULK1 IL-3 HSPC LT-HSC ILV BFU-E CFU-E BCR-ABL FIP200 vacuolar-ATPase Vps34 SQSTM1 Grb10 S6K PI3P RHEB FRB CFU-MK UVRAG WIPI Multipotent progenitor GABARAPL1 MAP1S AML Dfcp1 PML-RARα unc-51-like kinase 1 breakpoint cluster region-Abelson lysosome-associated membrane protein 2a VMP1 Janus kinase natural killer 3-methyladenine eukaryotic translation initiation factor 4E 5′-adenosine monophosphate-activated protein kinase atRA Chaperone-mediated autophagy PMA MAPK/ERK kinase Mdm2 ROS S6 kinase t-SNARE v-SNARE intraluminal vesicles Adenosine Triphosphate ATP arsenic trioxide all-trans retinoic acid STAT cyclooxygenase Autophagy erythropoietin inflammation Interleukin 3 multivesicular bodies event free survival overall survival Sickle cell disease Thrombopoietin Hematopoietic differentiation forkhead box O3 cluster of differentiation Ras homolog enriched in brain World Health Organization Cancer therapy Hematopoietic stem cell Hematopoietic stem and progenitor cell Leukemia stem cells Mesenchymal stem cell myelodysplastic syndrome endoplasmic reticulum hypoxia-inducible factor 1α granulocyte-macrophage colony-stimulating factor granulocyte colony-stimulating factor Stem Cell Factor G-CSF phorbol myristate acetate phosphatidylinositol phosphatidylinositol-3-phosphate phosphoinositide 3-kinase Diffuse large B-cell lymphoma leukemia acute myeloid leukemia Mixed lineage leukemia Acute lymphoblastic leukemia Acute megakaryoblastic leukemia Chronic myeloid leukemia Acute promyelocytic leukemia CAR macrophage colony-stimulating factor signal transducers and activators of transcription MEK endosomal sorting complex required for transport Earle's balanced salt solution Tyrosine kinase inhibitor Multiple myeloma MicroRNA knock-out mammalian target of rapamycin Mammalian target of rapamycin complex heme oxygenase 1 ALL Hemoglobin FK506-binding protein Vesicle-associated membrane protein Heat shock cognate protein 70 Autophagy-related proteins common lymphoid progenitor common myeloid progenitor JAK WHO extracellular signal-regulated kinase GABARAP Glucocorticoid Reactive oxygen species soluble N-ethylmaleimide-sensitive factor attachment protein receptor

Related Topics

Health Sciences Pharmacology, Toxicology and Pharmaceutical Science Pharmacology

Autophagy as a pharmacological target in hematopoiesis and hematological disorders

Authors

Marion Orsini, Franck Morceau, Mario Dicato, Marc Diederich,