| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8524044 | Biochemical Pharmacology | 2018 | 46 Pages |
Keywords
LBPTyk2IgG4SAAJAK1Janus kinase 1IgG2aAUClastIL-22HT-29HEK293EC50kDaHRPDSSLOQDMEMIL-22R1IL-10R2STAT3Cmaxt1/2immunoglobulin G4interleukinInterleukin 22Regenerativetumor necrosis factor alphatyrosine kinase 2serum amyloid ADendritic cellshuman embryonic kidney cellsIntestinal epithelial cellspharmacodynamicPharmacologypharmacokineticTNF-αsignal transducer and activator of transcription 3lower limit of detectionDulbecco’s modified eagle’s mediumarea under concentration-time curvehalf maximal effective concentrationhalf lifeHorseradish peroxidaselipopolysaccharide binding proteinFc fusion proteintotal clearancegastro-intestinal
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Authors
Eric G. Stefanich, Julie Rae, Siddharth Sukumaran, Jeff Lutman, Annemarie Lekkerkerker, Wenjun Ouyang, Xiaoting Wang, Donna Lee, Dimitry M. Danilenko, Lauri Diehl, Kelly M. Loyet, Ann Herman,