Tanshinone IIA suppresses FcÎµRI-mediated mast cell signaling and anaphylaxis by activation of the Sirt1/LKB1/AMPK pathway

Article ID	Journal	Published Year	Pages	File Type
8524052	Biochemical Pharmacology	2018	37 Pages	PDF

Keywords

LKB1 Ac-Lys PTP1B LTC4 BMMCs PLCγ IKK PGC-1α PGD2 mTOR HSA AMPK NF-κB Jnk PI3K ACC IL-6 peroxisome proliferator-activated receptor gamma coactivator 1-alpha AMP-activated protein kinase c-Jun N-terminal kinase IκB kinase MAPK PCA human serum albumin Passive cutaneous anaphylaxis acetyl-CoA carboxylase interleukin-6 LAT Bone marrow-derived mast cells nuclear factor kappa B Phosphatidylinositol 3-kinase phospholipase Cγ Leukotriene C4 Linker for activation of T cells mammalian target of rapamycin mitogen-activated protein kinase Prostaglandin D2 liver kinase B1

Related Topics

Health Sciences Pharmacology, Toxicology and Pharmaceutical Science Pharmacology

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Tanshinone IIA suppresses FcÎµRI-mediated mast cell signaling and anaphylaxis by activation of the Sirt1/LKB1/AMPK pathway

Authors

Xian Li, Soon Jin Park, Fansi Jin, Yifeng Deng, Ju Hye Yang, Jae-Hoon Chang, Dong-Young Kim, Jung-Ae Kim, Youn Ju Lee, Makoto Murakami, Kun Ho Son, Hyeun Wook Chang,