Dopamine promotes cellular iron accumulation and oxidative stress responses in macrophages

Article ID	Journal	Published Year	Pages	File Type
8524353	Biochemical Pharmacology	2018	32 Pages	PDF

Keywords

Hprt ferroportin-1 SLC DRD MnSOD COMT HIF-1α DMT1 Heme oxygenase-1 IRP MAO TfR1 NTBI LCN2 Fpn1 FTH BMDMs FTL TBI Catechol-O-Methyl-Transferase LIP qRT-PCR PMS DFO Nrf2 DOPA HO-1 NAC Deferoxamine N-acetylcysteine ROS Iron Labile iron pool Parkinson’s disease Oxidative stress solute carrier Dopamine dihydroxyphenylalanine Ferritin Heavy Chain Ferritin Light Chain Mitochondrial superoxide dismutase nuclear factor erythroid 2-related factor Non-transferrin bound iron Hypoxia-inducible factor lipocalin-2 Macrophage peritoneal macrophages Divalent metal transporter 1 monoamine oxidase inhibitor monoamine oxidase norepinephrine wild-type ARE hypoxanthine phosphoribosyltransferase quantitative real-time PCR iron regulatory protein catecholamine Reactive oxygen species Dopamine receptor transferrin receptor 1

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Dopamine promotes cellular iron accumulation and oxidative stress responses in macrophages

Authors

Stefanie Dichtl, David Haschka, Manfred Nairz, Markus Seifert, Chiara Volani, Oliver Lutz, Günter Weiss,