Camptothecin and its analog SN-38, the active metabolite of irinotecan, inhibit binding of the transcriptional regulator and oncoprotein FUBP1 to its DNA target sequence FUSE

Article ID	Journal	Published Year	Pages	File Type
8524460	Biochemical Pharmacology	2017	38 Pages	PDF

Keywords

SN-38 (PubChem CID: 104842)SN-38 Camptothecin (PubChem CID: 24360)AlphaScreen FUBP1 HCC camptothecin

Related Topics

Health Sciences Pharmacology, Toxicology and Pharmaceutical Science Pharmacology

Preview

Camptothecin and its analog SN-38, the active metabolite of irinotecan, inhibit binding of the transcriptional regulator and oncoprotein FUBP1 to its DNA target sequence FUSE

Authors

Sabrina Khageh Hosseini, Stefanie Kolterer, Marlene Steiner, Viktoria von Manstein, Katharina Gerlach, Jörg Trojan, Oliver Waidmann, Stefan Zeuzem, Jörg O. Schulze, Steffen Hahn, Dieter Steinhilber, Volker Gatterdam, Robert Tampé, Ricardo M. Biondi,