| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8530565 | Fitoterapia | 2018 | 10 Pages |
Abstract
33 jatrophane diterpenoids (1-33) isolated from Euphorbia helioscopia were evaluated for their lipid-lowering activity for the first time. Compound 21 showed remarkable lipid-lowering effect in vivo and could be served as a promising lead for development of new lipid-lowering agents.74
Keywords
HDLLDL-CLDLRHDL-CERKGADPHCHDEuphorbia helioscopiaCHOLMDRJatrophanesDMSOLPDsSDS-PAGESodium dodecyl sulfate polyacrylamide gel electrophoresiscoronary heart diseasecardiovascular diseaseDimethyl sulfoxideCVDlipoprotein-deficient serumhigh density lipoproteinlow density lipoproteinLDLMultidrug resistanceHyperlipidemiapolymerase chain reactionPCRLipid-loweringcholesterolhigh density lipoprotein cholesterollow density lipoprotein cholesterolglyceraldehyde-3-phosphate dehydrogenaseLDL receptorlow density lipoprotein receptor
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Authors
Jun Li, Hui-hui Li, Wen-qiong Wang, Wei-bin Song, Yi-ping Wang, Li-jiang Xuan,