7α,8α-Epoxynagilactones and their glucosides from the twigs of Podocarpus nagi: Isolation, structures, and cytotoxic activities

Eight previously undescribed 7α,8α-epoxynagilactones and its glucosides were isolated from the twigs of Podocarpus nagi. Compound 1 showed strong cytotoxic activities against three different types of human cancer cells. Further study indicated compound 1 might induce the cell to death via triggering apoptosis and arresting cell cycle at the G1 phase.79