Anti-inflammatory effects of luteolin: A review of in vitro, in vivo, and in silico studies

Article ID	Journal	Published Year	Pages	File Type
8532092	Journal of Ethnopharmacology	2018	17 Pages	PDF

Keywords

CREB Sirt1 STAT3 NF-κB PI3K MMP LPS CCL2 Jnk CXCL2 PRV NFAT MIP MYD88 GFP GSH HO-1 COX-2 HUVECS ICAM-1 HSP90 IFN-β HDAC SRC iNOS PGE2 MCP-1 IL-1β IκB AP-1 TLR PKC IKK HMGB1 Heme oxygenase-1 BMMCs chemokine (C-X-C motif) ligand 2 SOCS phorbol 12-myristate 13-acetate VCAM-1 IRF TBK1 IP-10 LTC4 Inflammatory signaling interferon regulatory transcription factor Proto-oncogene tyrosine-protein kinase NAD-dependent deacetylase sirtuin-1 Janus tyrosine kinase c-Jun N-terminal kinase ERK1/2 IκB kinase PMA MAPK ROS TRIF Adenosine Triphosphate ATP Akt myeloid differentiation primary response 88 Interferon-β TIR-domain-containing adapter-inducing interferon-β Interleukin-1β Syk Inflammatory diseases toll like receptor tumor necrosis factor-α TANK-binding kinase 1 TIMP SOD suppressor of cytokine signaling Human umbilical vein endothelial cells Bone marrow-derived mast cells NK cells Natural killer cells Superoxide dismutase spleen tyrosine kinase nuclear factor of activated T-cells TNF-α nuclear factor kappa B phosphatidylinositide 3-kinases Flavonoid lactate dehydrogenase LDH Luteolin Luteolin (PubChem CID: 5280445)Leukotriene C4 Lipopolysaccharides signal transducer and activator of transcription 3 Matrix metalloproteinases inhibitor of kappa B Tissue inhibitors of metalloproteinases Intercellular adhesion molecule 1 Nitric oxide Histone acetyltransferase histone deacetylase Pseudorabies virus macrophage inflammatory protein Heat shock protein 90 monocyte chemoattractant protein-1 activator protein green fluorescent protein interferon gamma-induced protein 10 cAMP response element-binding protein vascular cell adhesion protein 1 extracellular signal-regulated protein kinases 1 and 2 protein kinase B Protein kinase C mitogen-activated protein kinase Prostaglandin E2 JAK HAT chemokine (C-C motif) ligand 2 Glutathione Reactive oxygen species

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Anti-inflammatory effects of luteolin: A review of in vitro, in vivo, and in silico studies

Authors

Nur Aziz, Mi-Yeon Kim, Jae Youl Cho,