Chemical characterization and cerebroprotective effect of methanolic root extract of Colebrookea oppositifolia in rats

Article ID	Journal	Published Year	Pages	File Type
8532119	Journal of Ethnopharmacology	2018	46 Pages	PDF

Keywords

DPI NF-κB PBS LPS IL-6 DMEM CMC KCl LD50 DPPH ORAC TBA IC50 SDH TCA GSH FRAP EPM HWT GSSG TTC DTNB iNOS DCFH-DA RNS MECO IL-1β IL-10 AP-1 PARP PFT CPCSEA NG-nitro-l-arginine methyl ester IAEC FDA ICAM-I liquid chromatography mass spectroscopy 2-Thiobarbituric acid 2,3,5-triphenyltetrazolium chloride 5,5′-dithiobis-(2-nitrobenzoic acid)DMSO DNA Dulbecco's modified Eagle Medium I/R l-NAME LC-MS/MS ROS rt-PA Hydrogen peroxide elevated plus maze test enzyme linked immunosorbent assay EDTA Ethylenediaminetetraacetic acid trichloroacetic acid gamma amino butyric acid Ischemia reperfusion Cerebral ischemia Interleukin-10 interleukin-6 Interleukin-1β Transfer latency analysis of variance ANOVA ELISA Oxidative stress tumor necrosis factor-alpha standard error of mean Bilateral common carotid occlusion lethal dose 50%Dichloro-dihydro-fluorescein diacetate diphenylene iodonium Dimethyl sulfoxide electron transport chain Food and Drug Administration SOD inducible nitric oxide synthase Superoxide dismutase succinate dehydrogenase Stroke oxygen radical absorbance capacity Inhibitory Concentration 50%TNF-α Nuclear factor-kappa B phosphate buffer saline Recombinant tissue plasminogen activator Antioxidant activity lipopolysaccharide Neuroprotection SEM NAD Nitric oxide nicotinamide adenine dinucleotide H2O2 ETc activator protein-1 poly ADP-ribose polymerase ferric reducing antioxidant power reduced glutathione carboxy methyl cellulose Potassium chloride institutional animal ethics committee GABA glutathione disulphide glutathione reductase reactive nitrogen species Reactive oxygen species

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Chemical characterization and cerebroprotective effect of methanolic root extract of Colebrookea oppositifolia in rats

Authors

Gollapalle Lakshminarayanashastry Viswanatha, Marikunte V. Venkataranganna, Nunna Bheema Lingeswara Prasad, Shylaja Hanumanthappa,