Jianpi Jiedu decoction, a traditional Chinese medicine formula, inhibits tumorigenesis, metastasis, and angiogenesis through the mTOR/HIF-1Î±/VEGF pathway

Article ID	Journal	Published Year	Pages	File Type
8532130	Journal of Ethnopharmacology	2018	26 Pages	PDF

Keywords

4E-BP1 HIF-1α p70S6K TCM mTOR PBS 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2-H-tetrazolium bromide H&E MTT UPLC–MS/MS Angiogenesis IHC Immunohistochemistry ANOVA one-way analysis of variance Terminal deoxynucleotidyl transferase dUTP nick end labeling Tumorigenesis TUNEL Colorectal cancer Antitumor traditional Chinese medicine ultra-performance liquid chromatography tandem mass spectrometry hypoxia inducible factor-1α Vascular endothelial growth factor Vascular Endothelial Growth Factor (VEGF)Metastasis phosphate buffered solution mammalian target of rapamycin Hematoxylin and Eosin ribosomal protein S6 kinase CRC

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Jianpi Jiedu decoction, a traditional Chinese medicine formula, inhibits tumorigenesis, metastasis, and angiogenesis through the mTOR/HIF-1Î±/VEGF pathway

Authors

Weijun Peng, Shaofang Zhang, Zheyu Zhang, Panpan Xu, Dan Mao, Siqi Huang, Biyue Chen, Chunhu Zhang, Sifang Zhang,