Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8532160 | Journal of Ethnopharmacology | 2018 | 61 Pages |
Abstract
Cell cycle distribution of leukemia CCRF-CEM cells treated with bark extract of Curcuma longa rhizomes (CLR), Lycopersicon esculentum leaves (LEL), Psidium guajava bark (PGB) and doxorubicin at their IC50 values for 72â¯h: Upon treatment, CLR, LEL and PGB induced apoptosis cell cycle arrest in G0/G1 phase whilst doxorubicin induced S and G2/M arrest.173
Keywords
PGBPPTIC50ACPABCCPLARHLdichlorofluoresceinBcrpJC-1CLRDFAfluorescein isothiocynateAHTP-gpRFLMILCSLferrostatin-1ValinomycinH2DCFH-DAFITCPBSMDRDeferoxamineNCIMMPCPPLELEGFRDcf5,5′,6,6′-tetrachloro-1,1′,3,3′-tetraethylbenzimidazolylcarbocyanine iodideDMSOP-glycoproteinROSHydrogen peroxideIARC یا International Agency for Research on CancerApoptosisDoxorubicindimethylsufoxidephosphate buffer salinemulti-drug resistantNational Cancer InstituteH2O2Mitochondrial membrane potentialbreast cancer resistance proteinPropidium iodideGeneticinCameroonAdenosine triphosphate-binding cassetteReactive oxygen speciesEpidermal growth factor receptor
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Authors
Armelle T. Mbaveng, Hermione T. Manekeng, Gaelle S. Nguenang, Joachim K. Dzotam, Victor Kuete, Thomas Efferth,