Piper sarmentosum Roxb. confers neuroprotection on beta-amyloid (AÎ²)-induced microglia-mediated neuroinflammation and attenuates tau hyperphosphorylation in SH-SY5Y cells

Article ID	Journal	Published Year	Pages	File Type
8532442	Journal of Ethnopharmacology	2018	29 Pages	PDF

Keywords

DCM NFTs ATCC IL-1β Folin-Ciocalteu GAE tPCS LEA RT-PCR BV-2 cells GAPDH Aβ IC50 PID DPPH Na2CO3 PBS t-tau 3-(4,5-dimethylthiazol-2-yl)−2,5-diphenyltetrazolium bromide FRIM DMEM FBS 2,2-diphenyl-1-picrylhydrazyl DMSO Dulbecco's modified Eagle's medium MTT P/S Ethyl acetate Neuroinflammation Interleukin-1β Beta amyloid Alzheimer's disease analysis of variance ANOVA Enzyme-linked immunosorbent assay ELISA tumour necrosis factor-α standard error of mean CNS Dichloromethane Dimethyl sulfoxide conditioned media fetal bovine serum SH-SY5Y cells human neuroblastoma cells Cytokines central nervous system Correlation coefficient TNF-α Phosphate buffered saline Methanol American Tissue Culture Collection Total phenolic contents SEM Gallic acid equivalent MeOH neurofibrillary tangles Microglia Nitric oxide hexane Tau hyperphosphorylation reverse transcription-polymerase chain reaction Penicillin/streptomycin Vehicle control glyceraldehyde-3-phosphate dehydrogenase

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Piper sarmentosum Roxb. confers neuroprotection on beta-amyloid (AÎ²)-induced microglia-mediated neuroinflammation and attenuates tau hyperphosphorylation in SH-SY5Y cells

Authors

Emilia Tze Ying Yeo, Kelly Wang Ling Wong, Mun Ling See, Ka Yan Wong, Sook Yee Gan, Elaine Wan Ling Chan,