Protective effect of ethyl acetate fraction of Drynaria quercifolia against CCl4 induced rat liver fibrosis via Nrf2/ARE and NFÎºB signalling pathway

Article ID	Journal	Published Year	Pages	File Type
8532445	Journal of Ethnopharmacology	2018	10 Pages	PDF

Keywords

ECM α-Smooth muscle actin (α-SMA)MDA Tissue inhibitor of metalloproteinase-1 (TIMP-1)LC-QTOF-MS TIMP-1 INR H & E Kelch-like ECH-associated protein-1 CCl4 ALT iNOS NBT qRT-PCR GSH Nrf2 CAT LPS MMP HSC α-SMA NF-κB keap1 cDNA nitroblue tetrazolium TNF- α AST alanine transaminase ALP Alkaline phosphatase complementary deoxyribonucleic acid α-smooth muscle actin LOX IHC tissue inhibitor of metalloproteinase-1 Serum bilirubin analysis of variance ANOVA aspartate transaminase tumour necrosis factor-α prothrombin time SOD Hepatic stellate cells inducible nitric oxide synthase Superoxide dismutase Anti-inflammatory Nuclear factor erythroid 2-related factor 2 (Nrf2)antioxidant response element nuclear factor κB nuclear factor erythroid 2-related factor 2 Liver fibrosis lipoxygenase lipopolysaccharide extra cellular matrix malondialdehyde Matrix metalloproteinases International Normalized Ratio ARE Hematoxylin and Eosin quantitative real-time polymerase chain reaction Catalase reduced glutathione Carbon tetrachloride

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$Protective effect of ethyl acetate fraction of Drynaria quercifolia against CCl4 induced rat liver fibrosis via Nrf2/ARE and NFÎºB signalling pathway$

Authors

G.I. Anuja, V.J. Shine, P.G. Latha, S.R. Suja,