| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8532596 | Journal of Ethnopharmacology | 2018 | 33 Pages |
Abstract
HF administration was a valid therapeutic approach for DR treatment, oriented at the blockade of endoplasmic reticulum- and mitochondria-dependent oxidative stress-induced retinal neurodegeneration including RGC apoptosis.
Keywords
IGF-1IPLINLDCFDAHIF-1αBRBSTZGCLcyt-cRBGRGCFBGATF4random blood glucose2′,7′-dichlorofluorescin diacetateAUCC/EBP homologous proteinIPGTTMAPKROSHydrogen peroxideintraperitoneal glucose tolerance testEndoplasmic reticulum stressstreptozotocininsulin-like growth factor-1CHOPretinal degenerationdiabetic retinopathyretinal ganglion cellcytochrome chypoxia-inducible factor 1αactivating transcription factor 4fasting blood glucoseinner plexiform layerinner nuclear layerganglion cell layerBlood-retinal barrierarea under the curveH2O2postsynaptic density protein 95mitogen-activated protein kinaseReactive oxygen species
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Authors
Cheng Zhang, Yu Xu, Hor-Yue Tan, Sha Li, Ning Wang, Yinjian Zhang, Yibin Feng,