Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8533720 | Journal of Pharmacological and Toxicological Methods | 2018 | 35 Pages |
Abstract
Short-term delivery of adenine via precise gavage delivery induced a robust model with hallmarks of fibrotic kidney disease, had limited variance between animals, and no animal morbidity within the 20â¯days studied. This model represents a methodical alternative to long-term dietary dosing of adenine.
Related Topics
Health Sciences
Pharmacology, Toxicology and Pharmaceutical Science
Pharmacology
Authors
Chang Z. Zhu, Kelly J. Doyle, Arthur L. Nikkel, Lauren Olsen, Marian T. Namovic, Katherine Salte, Deborah Widomski, Zhi Su, Diana L. Donnelly-Roberts, Murali M. Gopalakrishnan, Steve McGaraughty,