Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8533800 | Journal of Pharmacological and Toxicological Methods | 2018 | 16 Pages |
Abstract
This study demonstrates a novel pharmacological method of assessing human serotonin transporter reuptake inhibition activity using commercially available JAR cells. Our results show that JAR cells provide an easily available and good alternative to using rat brain tissue and HEK293 cells, with the advantage of studying serotonin transporter reuptake inhibition in a human background.
Keywords
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Authors
Ann M. Decker, Bruce E. Blough,