Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8533837 | Journal of Pharmacological and Toxicological Methods | 2018 | 32 Pages |
Abstract
The analysis from the current study supports the strategic use of the anesthetized dog model early in the drug Discovery process for a comprehensive cardiovascular evaluation that can include left ventricular dP/dtmax with good translation to human.
Keywords
Related Topics
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Pharmacology, Toxicology and Pharmaceutical Science
Pharmacology
Authors
Yevgeniya E. Koshman, Brett R. Herzberg, Terese R. Seifert, James S. Polakowski, Scott W. Mittelstadt,