Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8533877 | Journal of Pharmacological and Toxicological Methods | 2018 | 19 Pages |
Abstract
Renal function assessment using TD-GFR is a valid method to improve preclinical drug discovery and development. Furthermore, TD-GFR method offers advantages in terms of reduced need for blood sampling and thus decreasing animal burden compared to standard procedures.
Related Topics
Health Sciences
Pharmacology, Toxicology and Pharmaceutical Science
Pharmacology
Authors
Thomas Mondritzki, Sarah M.L. Steinbach, Philip Boehme, Jessica Hoffmann, Maximilian Kullmann, Daniel Schock-Kusch, Julia Vogel, Peter Kolkhof, Peter Sandner, Erwin Bischoff, Jörg Hüser, Wilfried Dinh, Hubert Truebel,