Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8533891 | Journal of Pharmacological and Toxicological Methods | 2018 | 31 Pages |
Abstract
The present study highlights media formulation as an important consideration for cardiac safety testing with iPSC-CMs. Results described here suggest that media formulation influences both compound availability and baseline electrophysiological properties. Special attention should be paid to media for future iPSC-CM assays.
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Authors
Derek Schocken, Jayna Stohlman, Jose Vicente, Dulciana Chan, Dakshesh Patel, Murali Krishna Matta, Vikram Patel, Mathew Brock, Daniel Millard, James Ross, David G. Strauss, Ksenia Blinova,