Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8533921 | Journal of Pharmacological and Toxicological Methods | 2018 | 40 Pages |
Abstract
The data provide clear statistical insight into the translatability of Nav1.5 antagonism data generated in vitro to potential clinical outcomes. These results improve our ability to understand the liability posed by such activity in novel development compounds at an early stage.
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Authors
Stephen Jenkinson, Asser Bassyouni, Jason Cordes, Bernard Fermini, Donglin Guo, David M. Potter, David S. Ramirez, Jill Steidl-Nichols, Sunny Sun, Todd Wisialowski,