Targeting oncogenic transcription factors by polyphenols: A novel approach for cancer therapy

Article ID	Journal	Published Year	Pages	File Type
8536525	Pharmacological Research	2018	19 Pages	PDF

Keywords

NF-κB PI3K MMP CCL2 Jnk PHB PSA mTOR ICAM-1 TGFβ FAK FGF Mcl-1 Chrysin (PubChem CID: 5281607)iNOS PGE2 cox2 FOXO3a HIF-1α IAP ERα IKK Bcl2 ERK1 PARP IGF-1R IκBα CXCR2 Dnmt1 uPA SOCS3 FOXM1 c-FLIP CDK4 forkhead box protein M1 XIAP LRP4 DNA methyltransferase 1 Quercetin (PubChem CID: 5280343)Mangiferin (PubChem CID: 5281647)Honokiol (PubChem CID: 72303)Apigenin (PubChem CID: 5280443)inhibitory kappa B kinase Cryptotanshinone (PubChem CID: 160254)Wogonin (PubChem CID: 5281703)Shp1 Xanthohumol (PubChem CID: 639665)CDC25B PCNA LDL receptor related protein Janus kinase c-Jun N-terminal kinase hTERT Mdm2 ROS STAT proliferative cell nuclear antigen AIF Ellagic Acid (PubChem CID: 5281855)Ursolic acid (PubChem CID: 64945)inflammation epithelial to mesenchymal transition Bax Berberine (PubChem CID: 2353)Transforming Growth Factor Beta Natural compounds Telomerase reverse transcriptase tumor necrosis factor alpha EMT forkhead box O3 Resveratrol (PubChem CID: 445154)Rutin (PubChem CID: 5280805)Cancer suppressor of cytokine signaling 3 inducible nitric oxide synthase cyclooxygenase 2 cyclin-dependent kinase 2 apoptosis-inducing factor Fibroblast Growth Factors Transcription factors Vascular endothelial growth factor Vascular Endothelial Growth Factor (VEGF)insulin-like growth factor 1 TNF-α nuclear factor-κB phosphoinositide 3-kinase urokinase-type plasminogen activator Luteolin (PubChem CID: 5280445)chemokine ligand 2 matrix metalloproteinase Signal transducer and activator of transcription Metastasis Prohibitin mouse double minute 2 homolog Intercellular adhesion molecule 1 mammalian target of rapamycin prostate-specific antigen Bcl-2-associated X protein X-linked Inhibitor of Apoptosis Protein protein kinase A Prostaglandin E2 poly (ADP-ribose) polymerase Polyphenols JAK Curcumin (PubChem CID: 969516)focal adhesion kinase cyclin-dependent kinase 4 Reactive oxygen species Estrogen receptor alpha androgen receptors

Related Topics

Health Sciences Pharmacology, Toxicology and Pharmaceutical Science Pharmacology

Targeting oncogenic transcription factors by polyphenols: A novel approach for cancer therapy

Authors

Chitra Rajagopal, Manendra Babu Lankadasari, Jesil Mathew Aranjani, K.B. Harikumar,