| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8536550 | Pharmacological Research | 2018 | 35 Pages |
Keywords
TNF-AMSEC50APPIL-1βHEK293MMSECDR-SBTDP-43Presenilin-1TACEMTDHMDBAβ1-42NF-κβIAPPADAS-CogCDERTREM218F-FDG-PETCD33late-onset ADUbiquitin/proteasome systemFDATGF-βTNFRsCPCSNPsNSAIDSPPAR-γIL-6BACE1presenilin-2Clinical trialsApoeapolipoprotein ESilkClinicopathological correlationsMRIADAPTInterleukin-1-betainterleukin-6LoadFADAlzheimer’s diseasetransforming growth factor-betaMagnetic resonance imagingPositron emission tomographyMaximum tolerated doseNon-steroidal anti-inflammatory drugsCNSFood and Drug Administrationcentral nervous systemPMIMass spectrometrypharmacodynamicpharmacokineticFamilial ADnuclear factor kappa-light-chain-enhancer of activated B cellsCerebrospinal fluidCSFCenter for Drug Evaluation and ResearchGenome-wide association studiesGWASMini-Mental State Examinationhalf maximal effective concentrationPathophysiologyhuman metabolome databasePETamyloid precursor proteinPrecision medicineIslet amyloid polypeptideSingle nucleotide polymorphismhuman embryonic kidney 293triggering receptor expressed on myeloid cells 2TNF receptorsPeroxisome proliferator-activated receptor-γUPS
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Authors
Harald Hampel, Andrea Vergallo, Lisi Flores Aguilar, Norbert Benda, Karl Broich, A. Claudio Cuello, Jeffrey Cummings, Bruno Dubois, Howard J. Federoff, Massimo Fiandaca, Remy Genthon, Marion Haberkamp, Eric Karran, Mark Mapstone, George Perry,