Comparative clinical trial of the variability factors of the exposure indices used for the drug monitoring of two tacrolimus formulations in kidney transplant recipients

Article ID	Journal	Published Year	Pages	File Type
8536613	Pharmacological Research	2018	11 Pages	PDF

Keywords

CYP3A4 Cytochrome P450 3A5 biopsy proven acute rejection BPAR CYP3A5 TDM MDRD SAE GFR ABCB1 MMF PGP Cmax AUC HPLC–MS/MS P-glycoprotein EDTA ethylene diamine tetraacetic acid Prolonged release ITT Tacrolimus cytochrome P450 3A4 i.d.serious adverse events Pharmacokinetics drug exposure intention to treat mycophenolate mofetil area under the concentration time curve Glomerular filtration rate therapeutic drug monitoring NODAT Renal transplantation

Related Topics

Health Sciences Pharmacology, Toxicology and Pharmaceutical Science Pharmacology

Preview

Comparative clinical trial of the variability factors of the exposure indices used for the drug monitoring of two tacrolimus formulations in kidney transplant recipients

Authors

Pierre Marquet, Laetitia Albano, Jean-Baptiste Woillard, Lionel Rostaing, Nassim Kamar, Charlotte Sakarovitch, Philippe Gatault, Matthias Buchler, Bernard Charpentier, Eric Thervet, Elisabeth Cassuto,