| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8536766 | Pharmacology & Therapeutics | 2018 | 38 Pages |
Abstract
In addition, by taking part in all the major epigenetic and post-transcriptional programs in the cell, long non-coding RNAs are emerging as key regulators of stress responses and therefore they are important non-genetic players in cancer development and progression. Here I discuss the role of lncRNAs in cancer and their promises and pitfalls as biomarkers and therapeutic targets.
Keywords
ncRNAsBANCRNEAT1ZEBERVLTRUCA1PDXPPMOMITFLNAASOTSSLncRNA-ATBzinc finger E-box-binding homeoboxFDAlncRNAPNAMYCPMOAntisense oligonucleotidesshort interfering RNALong non-coding RNAsnon-coding RNAssiRNATGF-betaribonucleic acidRNALocked nucleic acidsPeptide nucleic acidsepithelial to mesenchymal transitionCETPatient derived xenograftLong terminal repeatEMTRISCTargeted therapyKnock-downFood and Drug AdministrationTranscriptional start siteCancerPhosphorothioatePhosphorodiamidate morpholino oligomerRNA-Induced Silencing ComplexTherapy resistanceBiomarkers
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Authors
Eleonora Leucci,