Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8541285 | Drug Invention Today | 2013 | 8 Pages |
Abstract
Preliminary phytochemical evaluation shows the presence of various bioactive constituents. Acute toxicity study reveals that LD50 of AEGS and EEGS is greater than 2000 mg/kg body weight (b wt) in fasted female rats and can be classified under category 5. The 28-day repeated oral toxicity study justified that the No Observed Adverse Effect Level (NOAEL) of G. serrulata DC (GS) is greater than 800 mg/kg b wt/day P.O in rats. There were no delayed effects in GS satellite group. In conclusion GS was found to be non-toxic in tested doses and experimental conditions.
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Authors
Irisappan Sarath Chandiran, Korlakunta Narasimha Jayaveera, Shaik Karimulla,