Article ID Journal Published Year Pages File Type
8541285 Drug Invention Today 2013 8 Pages PDF
Abstract
Preliminary phytochemical evaluation shows the presence of various bioactive constituents. Acute toxicity study reveals that LD50 of AEGS and EEGS is greater than 2000 mg/kg body weight (b wt) in fasted female rats and can be classified under category 5. The 28-day repeated oral toxicity study justified that the No Observed Adverse Effect Level (NOAEL) of G. serrulata DC (GS) is greater than 800 mg/kg b wt/day P.O in rats. There were no delayed effects in GS satellite group. In conclusion GS was found to be non-toxic in tested doses and experimental conditions.
Related Topics
Health Sciences Pharmacology, Toxicology and Pharmaceutical Science Pharmacology, Toxicology and Pharmaceutics (General)
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